Magnetic Amine Activated Resin is used to make magnetic chromatography adsorbents. It forms chemically stable amide linkages with ligands containing carboxyl groups. It has a long spacer (9 atoms). After binding of target molecules, the magnetic resin can be readily isolated from the biological feedstocks with the aid of a magnet.
Amine-activated agarose can be used for the immobilization of carboxyl containing, or aldehyde containing molecules. The coupling chemistry is carbodiimide-based or reduced amination based and is a successful and well-documented technique.