IEX Big Bead Resins

Protein Ark’s Fastback Q, DEAE, SP & CM Big Bead and Fastback Q, DEAE, SP & CM Big Bead Plus resins are a group of ion exchange chromatography media with large particle sizes (100 – 350 m). The base matrix shows excellent flow property and stable physical property. 

The above ion-exchange chromatography media is particularly suitable for large-scale purification of biological molecules from viscous and/or crude culture broths or for high speed flow-through polishing applications in which impure components are chromatographically adsorbed from the main product stream. 

This group of ion-exchange media has a balanced design among ligand density, loading capacity and separation power of individual components for large-scale biomanufacturing applications. Fastback IEX Big Bead Plus offers increased binding capacity and faster binding kinetics than Fastback IEX Big Beads resin. 

The base matrix of Fastback Big Bead is made of highly cross-linked agarose with excellent flow property. The Fastback Big Bead Plus is made of highly cross-linked agarose grafted with dextran for increased binding capacity. They are very stable to most of the chemical conditions experienced in the bioprocessing industry.